Janssen Pharmaceutica

Partner Presentation

Janssen RD is a subsidiary of the global pharmaceutical, medical devices and consumer packaged goods manufacturer Johnson & Johnson. Janssen Research and Development is responsible for discovering and developing pharmaceutical drugs and has research sites located in Beerse, Belgium, Raritan, New Jersey, Spring House, Pennsylvania, La Jolla, California and Toledo, Spain. The company?s division in Beerse, Belgium is known as Janssen Research and Development, Janssen Pharmaceutica NV with a strong focus on neuroscience research efforts. The site in Beerse has a long-standing interest in psychiatric disorders and has been the origin of the prototypic first- and second-generation antipsychotics Haloperidol and Risperdal, respectively.

The Neurosciences team at Beerse is part of a Global Neurosciences Organization and currently has responsibility for Research and Early development and as such identifies small molecules which are then progressed into development up to and including Phase IIa efficacy studies.

Accordingly, the Neurosciences Research group in Beerse has many of the skills sets required to complement the cross-functional and translational nature of the IMI Call. For example, the preclinical research team contains expertise in cellular assays, in vitro electrophysiological techniques and functional genomics along with in vivo groups experienced at using in EEG and behavioral pharmacology to characterize pharmacological responses. These methodologies are used to inform early human (Phase 0) studies conducted within the Experimental Medicine group. Over-arching all these teams is the Statistical group which provided on-going support for study design and data analysis.